From Northern Pinellas County:

Drive south on U.S. 19
Turn left at Sunset Point Road
Sunset Point Road will turn into Main Street
Main Street will turn into Bayshore Drive
The Spa will be in front of you

From Southern Pinellas County:

Drive north on U.S. 19
Turn right at Sunset Point Road
Sunset Point Road will turn into Main Street
Main Street will turn into Bayshore Drive
The Spa will be in front of you

From Tampa:

Drive south on I-275
Merge onto Memorial Highway / FL-60
Take SR-60 West via the exit on your left
Merge onto FL-60
Turn right at Bayshore Boulevard
Turn right at Bayshore Drive North