Drive south on U.S. 19
Turn left at Sunset Point Road
Turn right at McMullen Booth Road
U-Turn at Kapok Kove Drive
The Hampton will be on your right before Ruth Eckerd Hall

From Southern Pinellas County:

Drive north on U.S. 19
Turn right at Drew Street
Turn left at McMullen Booth Road
The Hampton will be on your right before Ruth Eckerd Hall

From Tampa:

Drive south on I-275
Take exit 39 onto Memorial Highway / FL-60 West toward the Tampa Airport / Clearwater
Exit at SR-60 West on the left hand side toward Clearwater
Merge onto Fl-60
Turn right at McMullen Booth Road
The Hampton will be on your right before Ruth Eckerd Hall